"I’ve been using Affimer® technology in my research for the past year and the data generated has been remarkable. My interest lies in understanding the mechanisms for blood clot formation and breakdown with the long-term aim of reducing heart attacks and strokes in high risk patients. A number of Affimer candidates have shown significant effects on the clotting process, which will help to develop novel therapeutic targets aiming to reduce thrombosis risk."
Dr Ramzi Ajjan
Associate Professor / Consultant, Diabetes and Endocrinology, University of Leeds and Leeds NHS Trust
Our research interests lie in studying the function of FcgR’s in autoimmune and inflammatory diseases. The Affimer candidates we’ve isolated have shown remarkable specificity and have proved useful not only as detection tools, but also for blocking receptor function. Furthermore, crystallisation of Affimer molecules with the receptors have identified allosteric inhibitors. Overall we’re delighted with the results and hope to develop them into therapeutics
Professor Anne W Morgan
Hon. Consultant Rheumatologist, University of Leeds
We use Affimer technology in a synthetic biology approach to design disease resistance in plants, focussing on the powdery mildew fungus. Using Affimer reagents to target virulence components, we have been able to obtain very promising results that may allow us to take this serious pathogen out of the game
Professor, Department of Plant and Environmental Sciences, University of Copenhagen